Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.3
USERS' SCORE
Moderately Good
Based on 12 Reviews
7.9
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Lactobacillus acidophilus (La-14)
2 Billion CFU
*
Top Medical Research Studies
9.5
In our clinical trial, we examined the effects of a probiotic combination of Lactobacillus acidophilus and L. plantarum on patients with diarrhea-predominant irritable bowel syndrome (IBS-D). We randomly assigned 100 participants to standard IBS treatment or the same treatment plus probiotics over 12 weeks.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
Read More
7
We explored the effectiveness of a two-strain mixture of Lactobacillus acidophilus for patients with irritable bowel syndrome over eight weeks. In a well-structured trial involving 80 participants, we compared the probiotic to a placebo.
While both groups reported improvements in abdominal pain, we didn’t find significant differences between them regarding pain relief. However, the acidophilus group experienced notable reductions in flatus and overall discomfort.
This suggests that Lactobacillus acidophilus could be a valuable option for symptom management despite no major advantages in abdominal pain.
While both groups reported improvements in abdominal pain, we didn’t find significant differences between them regarding pain relief. However, the acidophilus group experienced notable reductions in flatus and overall discomfort.
This suggests that Lactobacillus acidophilus could be a valuable option for symptom management despite no major advantages in abdominal pain.
Read More
9
We investigated the effects of two probiotic strains, DDS-1 and UABla-12, on abdominal pain and symptoms in people with irritable bowel syndrome (IBS). In a well-structured study involving 330 participants, those receiving probiotics experienced significant improvements in pain severity compared to a placebo group.
The DDS-1 strain showed a 52.3% response rate, while UABla-12 had a 28.2% response. Both probiotics also improved overall IBS symptoms, bowel consistency, and quality of life measures.
These findings suggest that probiotics could be a beneficial option for managing IBS symptoms.
The DDS-1 strain showed a 52.3% response rate, while UABla-12 had a 28.2% response. Both probiotics also improved overall IBS symptoms, bowel consistency, and quality of life measures.
These findings suggest that probiotics could be a beneficial option for managing IBS symptoms.
Read More
Most Useful Reviews
9
Helps with diarrhea
I purchased two bottles of this product. Initially, I took one pill and then increased to one in the morning and two in the evening. It's really helpful for my irritable bowel syndrome and has also benefited an elder in my family with chronic diarrhoea.
Read More
9
Enhanced bowel movements
After a week of taking one tablet before bed, my bowel movements have improved, and my stools are banana-shaped. It is more effective than yoghurt and other similar products.
Read More
9
Daily bowel movements
Previously, I had bowel movements only twice a week at most. Since I started this product, I now have daily bowel movements and will continue using it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.3
- All Researches
9.5
In our clinical trial, we examined the effects of a probiotic combination of Lactobacillus acidophilus and L. plantarum on patients with diarrhea-predominant irritable bowel syndrome (IBS-D). We randomly assigned 100 participants to standard IBS treatment or the same treatment plus probiotics over 12 weeks.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
Read More
9.5
This randomized, single-blinded trial evaluated the impact of probiotics, specifically Lactobacillus acidophilus and plantarum, on patients with diarrhea-predominant irritable bowel syndrome (IBS-D).
We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.
Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.
Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
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9
Probiotic milk improves IBS symptoms
We examined the effects of a daily cultured milk drink containing Lactobacillus acidophilus on individuals with constipation-predominant irritable bowel syndrome (IBS-C). Over 30 days, participants reported significant relief in constipation symptoms alongside improved intestinal transit time and decreased fecal pH.
Notably, the pro-inflammatory cytokines levels also dropped significantly, indicating a positive immune response. These results suggest that incorporating probiotic-rich cultured milk drinks might serve as a helpful addition to treat this condition effectively.
Notably, the pro-inflammatory cytokines levels also dropped significantly, indicating a positive immune response. These results suggest that incorporating probiotic-rich cultured milk drinks might serve as a helpful addition to treat this condition effectively.
Read More
9
We investigated the effects of two probiotic strains, DDS-1 and UABla-12, on abdominal pain and symptoms in people with irritable bowel syndrome (IBS). In a well-structured study involving 330 participants, those receiving probiotics experienced significant improvements in pain severity compared to a placebo group.
The DDS-1 strain showed a 52.3% response rate, while UABla-12 had a 28.2% response. Both probiotics also improved overall IBS symptoms, bowel consistency, and quality of life measures.
These findings suggest that probiotics could be a beneficial option for managing IBS symptoms.
The DDS-1 strain showed a 52.3% response rate, while UABla-12 had a 28.2% response. Both probiotics also improved overall IBS symptoms, bowel consistency, and quality of life measures.
These findings suggest that probiotics could be a beneficial option for managing IBS symptoms.
Read More
9
We investigated how probiotics impact symptoms of irritable bowel syndrome (IBS), especially in patients with small intestinal bacterial overgrowth (SIBO).
In a unique study featuring 26 IBS patients, those with SIBO experienced a remarkable 71.3% reduction in symptoms after taking a specific probiotic mix for 30 days.
Meanwhile, patients without SIBO showed only a 10.6% decrease. We noted significant improvements in satisfaction with bowel function, particularly in those with constipation-predominant IBS, regardless of SIBO status.
In a unique study featuring 26 IBS patients, those with SIBO experienced a remarkable 71.3% reduction in symptoms after taking a specific probiotic mix for 30 days.
Meanwhile, patients without SIBO showed only a 10.6% decrease. We noted significant improvements in satisfaction with bowel function, particularly in those with constipation-predominant IBS, regardless of SIBO status.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 12 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Helps with diarrhea
I purchased two bottles of this product. Initially, I took one pill and then increased to one in the morning and two in the evening. It's really helpful for my irritable bowel syndrome and has also benefited an elder in my family with chronic diarrhoea.
Read More
9
Enhanced bowel movements
After a week of taking one tablet before bed, my bowel movements have improved, and my stools are banana-shaped. It is more effective than yoghurt and other similar products.
Read More
9
Daily bowel movements
Previously, I had bowel movements only twice a week at most. Since I started this product, I now have daily bowel movements and will continue using it.
Read More
9
Effective treatment
Recommended. It helped my irritable bowel syndrome.
Read More
6
Beneficial for flatulence
5 people found this helpful
I noticed benefits for my irritable bowel and flatulence.
Read More
Frequently Asked Questions
9
Enhanced bowel movements
After a week of taking one tablet before bed, my bowel movements have improved, and my stools are banana-shaped. It is more effective than yoghurt and other similar products.
9
Daily bowel movements
Previously, I had bowel movements only twice a week at most. Since I started this product, I now have daily bowel movements and will continue using it.
7.5
Long-term intestinal health
1 people found this helpful
I bought this for my husband to maintain his intestinal health as he has irritable bowel syndrome. Continuous use is necessary for noticeable effects.
9
Helps with diarrhea
I purchased two bottles of this product. Initially, I took one pill and then increased to one in the morning and two in the evening. It's really helpful for my irritable bowel syndrome and has also benefited an elder in my family with chronic diarrhoea.
7.5
Stomach condition improved
6 people found this helpful
Over the past few years, I've suffered from an irritable bowel, experiencing painful stomach issues and frequent trips to the toilet. After researching, I found that Lactobacillus acidophilus was beneficial. Initially, I consumed yoghurt, which helped slightly, but I've since switched to this product, leading to significant improvement. My stomach pain has greatly diminished, and I rarely experience the distressing symptoms I once had.
9
Helps regulate bowels
1 people found this helpful
I have irritable bowel syndrome, and this product significantly helps to regulate my bowels. My gastroenterologist recommended ongoing use of a probiotic, and I've had great success with this one.
2
Mixed results
1 people found this helpful
I'm not sure about its effectiveness for my irritable bowel syndrome. While it’s kept in the refrigerator, it has a peculiar odour. I make an effort to consume it daily, but perhaps I'm not suited to it.
8
Effectively reduces diarrhea
1 people found this helpful
This is beneficial for irritable bowel syndrome, particularly for reducing diarrhoea. It prevents urgent bowel movements after meals and aids in forming loose stools. I recommend those with long-term diarrhoea consume 3-4 pieces daily between meals.
9.5
In our clinical trial, we examined the effects of a probiotic combination of Lactobacillus acidophilus and L. plantarum on patients with diarrhea-predominant irritable bowel syndrome (IBS-D). We randomly assigned 100 participants to standard IBS treatment or the same treatment plus probiotics over 12 weeks.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
9
We investigated the effects of two probiotic strains, DDS-1 and UABla-12, on abdominal pain and symptoms in people with irritable bowel syndrome (IBS). In a well-structured study involving 330 participants, those receiving probiotics experienced significant improvements in pain severity compared to a placebo group.
The DDS-1 strain showed a 52.3% response rate, while UABla-12 had a 28.2% response. Both probiotics also improved overall IBS symptoms, bowel consistency, and quality of life measures.
These findings suggest that probiotics could be a beneficial option for managing IBS symptoms.
The DDS-1 strain showed a 52.3% response rate, while UABla-12 had a 28.2% response. Both probiotics also improved overall IBS symptoms, bowel consistency, and quality of life measures.
These findings suggest that probiotics could be a beneficial option for managing IBS symptoms.
8
We investigated the impact of multispecies probiotics, including Lactobacillus acidophilus, in treating irritable bowel syndrome (IBS). In a randomized, double-blind study with 49 participants, those taking probiotics experienced significantly more symptom relief than those on a placebo after four weeks.
The probiotics not only eased abdominal discomfort and bloating but also positively altered gut bacteria. Our findings suggest that multispecies probiotics could be a valuable option for managing IBS symptoms.
The probiotics not only eased abdominal discomfort and bloating but also positively altered gut bacteria. Our findings suggest that multispecies probiotics could be a valuable option for managing IBS symptoms.
7
Probiotics improve mood and IBS symptoms
We investigated how a probiotic-rich cultured milk drink impacts depression and quality of life among irritable bowel syndrome (IBS) patients. Over 12 weeks, 110 participants consumed the milk, which contained Lactobacillus acidophilus and Lactobacillus paracasei.
Although depression scores decreased for those with subthreshold depression using the probiotics, only these participants showed a significant increase in serotonin levels. Meanwhile, quality of life and IBS severity improved across all groups.
In conclusion, probiotics may help manage mood and IBS symptoms in affected individuals.
Although depression scores decreased for those with subthreshold depression using the probiotics, only these participants showed a significant increase in serotonin levels. Meanwhile, quality of life and IBS severity improved across all groups.
In conclusion, probiotics may help manage mood and IBS symptoms in affected individuals.
References
- Gąsiorowska A, Romanowski M, Walecka-Kapica E, Kaczka A, Chojnacki C, et al. Efficacy and Safety of a Mixture of Microencapsulated Sodium Butyrate, Probiotics, and Short Chain Fructooligosaccharides in Patients with Irritable Bowel Syndrome-A Randomized, Double-Blind, Placebo-Controlled Study. J Clin Med. 2024;14. 10.3390/jcm14010006
- Sarkawi M, Raja Ali RA, Abdul Wahab N, Abdul Rathi ND, Mokhtar NM. A randomized, double-blinded, placebo-controlled clinical trial on Lactobacillus-containing cultured milk drink as adjuvant therapy for depression in irritable bowel syndrome. Sci Rep. 2024;14:9478. 10.1038/s41598-024-60029-2
- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;72:233.
- Chang YH, Choi YJ, Shin CM, Moon JS, Kim TY, et al. Efficacy of Quadruple-coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study. J Neurogastroenterol Motil. 2024;30:73. 10.5056/jnm23036
- Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. 10.33029/0042-8833-2023-92-4-92-103
- Cocetta V, Giacomini I, Tinazzi M, Berretta M, Quagliariello V, et al. Maintenance of intestinal epithelial barrier integrity by a combination of probiotics, herbal extract, and vitamins. Minerva Pediatr (Torino). 2023. 10.23736/S2724-5276.23.07128-8
- Mokhtar NM, Jaafar NM, Alfian E, Mohd Rathi ND, Abdul Rani R, et al. Clinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with Lactobacillus-containing cultured milk drink. Acta Gastroenterol Belg. 2021;84:585. 10.51821/84.4.009
- Skrzydło-Radomańska B, Prozorow-Król B, Cichoż-Lach H, Majsiak E, Bierła JB, et al. The Effectiveness of Synbiotic Preparation Containing and Probiotic Strains and Short Chain Fructooligosaccharides in Patients with Diarrhea Predominant Irritable Bowel Syndrome-A Randomized Double-Blind, Placebo-Controlled Study. Nutrients. 2020;12. 10.3390/nu12071999
- Maixent JM, Pons O, Sennoune SR, Sadrin S. Clinical effects of Lactobacillus strains as probiotics in the treatment of irritable bowel syndrome. Results from the LAPIBSS trial: Future objectives. Cell Mol Biol (Noisy-le-grand). 2020;66:211.
- Martoni CJ, Srivastava S, Leyer GJ. DDS-1 and UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial. Nutrients. 2020;12. 10.3390/nu12020363
- Sadrin S, Sennoune S, Gout B, Marque S, Moreau J, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis. 2020;52:534. 10.1016/j.dld.2019.12.009
- Preston K, Krumian R, Hattner J, de Montigny D, Stewart M, et al. Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms: a double-blind, randomised, placebo-controlled study. Benef Microbes. 2018;9:697. 10.3920/BM2017.0105
- Leventogiannis K, Gkolfakis P, Spithakis G, Tsatali A, Pistiki A, et al. Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth. Probiotics Antimicrob Proteins. 2019;11:627. 10.1007/s12602-018-9401-3
- Sadrin S, Sennoune SR, Gout B, Marque S, Moreau J, et al. Lactobacillus acidophilus versus placebo in the symptomatic treatment of irritable bowel syndrome: the LAPIBSS randomized trial. Cell Mol Biol (Noisy-le-grand). 2017;63:122. 10.14715/cmb/2017.63.9.21
- Bogovič Matijašić B, Obermajer T, Lipoglavšek L, Sernel T, Locatelli I, et al. Effects of synbiotic fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis ssp. lactis BB-12 on the fecal microbiota of adults with irritable bowel syndrome: A randomized double-blind, placebo-controlled trial. J Dairy Sci. 2016;99:5008. 10.3168/jds.2015-10743
- Yoon H, Park YS, Lee DH, Seo JG, Shin CM, et al. Effect of administering a multi-species probiotic mixture on the changes in fecal microbiota and symptoms of irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Biochem Nutr. 2015;57:129. 10.3164/jcbn.15-14
- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;73:233.
- Shin SY, Park S, Moon JM, Kim K, Kim JW, et al. Compositional Changes in the Gut Microbiota of Responders and Non-responders to Probiotic Treatment Among Patients With Diarrhea-predominant Irritable Bowel Syndrome: A Post Hoc Analysis of a Randomized Clinical Trial. J Neurogastroenterol Motil. 2022;28:642. 10.5056/jnm21202
- Yoon JS, Sohn W, Lee OY, Lee SP, Lee KN, et al. Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Gastroenterol Hepatol. 2014;29:52. 10.1111/jgh.12322
